EXPERIMENTAL SURGERY IN ORTHOTOPIC LIVER TRANSPLANTATION (OLTX: ANATOMO-PATHOLOGIC CORRELATION.

Orthotopic liver transplantation (OLTx) in non-cirrhotic portal hypertension secondary to ADAMTS13 deficiency.

Non-cirrhotic intrahepatic portal hypertension (NCIPH), also called idiopathic or benign, may lead to life-threatening complications. It is a rare indication for orthotopic liver transplantation (OLTx), although it may remain underdiagnosed. Overt symptoms of portal hy-pertension, predominantly variceal bleedings, misleadingly suggest that these patients are cirrhotic. Non-cir-rhotic intrahepat...

Orthotopic Liver Transplantation

Orthotopic Liver Transplantation

A 7-year-old girl with progressive ataxia, spasticity, supranuclear ophthalmoplegia, and sea-blue histiocytes in her bone marrow underwent orthotopic liver transplantation for hepatocellular carcinoma. After an initial period of stabilization, she has shown progression of neurologic symptoms with recurrence of storage material in the transplanted liver. Pediatrics 1986;77:104-106; lipidosis, se...

Aprotinin in orthotopic liver transplantation.

Aprotinin is a protease inhibitor isolated from bovine lungs and othcr lissues. Its biochcmical struc!Urc, a single-chain polypeptide of 6.5 12 kD , and biophysical properties are weH defined. I The activity of commcrcial preparations of apralini n is usually describcd in kallikrein inac ti valor unils (KIU) , 0. 1 million KIU being equivalent 102. 15 j-Lmol of apralinin per liter. Sy inhibitin...

Orthotopic Liver Transplantation in Rats

Clinical progress in the field of liver transplantation has been largely supported by animal models(1,2). Since the publication of the first orthotopic rat liver transplantation in 1979 by Kamada et al.(3), this model has remained the gold standard despite various proposed alternative techniques(4). Nevertheless, its broader use is limited by its steep learning curve(5). In this video paper,...